Kidney Stones

Dr. Michael AaronsonAfter passing my Internal Medicine Board Recertification, I started intensively studying for my Nephrology Board Exam. After reviewing the kidney stone section, I wanted to share some pearls of wisdom regarding the two common questions I often hear when evaluating a patient with kidney stones.

First, I want to make sure you know the difference between a urologist and a nephrologist because both specialties help patients with kidney stones. Urology is the branch of medicine that deals with the diagnosis and treatment of diseases of the urinary tract and urogenital system. Nephrology is the science that deals with the kidneys, especially their functions or diseases. Urologists perform surgery to remove stones. Nephrologists do not perform surgery. Instead, kidney doctors focus on why the patient is prone to get stones. This evaluation is called a "metabolic work up." Frequently the nephrologist and urologist work together to provide a patient with total kidney stone care.

The only universal recommendation I make to my kidney stone patients is that they need to drink enough water so that they produce more than two liters of urine per day. The water ingestion should be throughout the day. The urine concentration needs to be dilute so that the risk of kidney stone formation is decreased. Here's why: let's say a person is prone to make calcium oxalate stones — a frequent type of kidney stone. In order for the calcium to attach to the oxalate, the two molecules have to get "near enough" to each other.

| calcium --> <-- oxalate |

A concentrated urine. Easier for calcium and oxalate to find each other.

| calcium -->                              <--oxalate|
A dilute urine. Harder for calcium and oxalate to find each other. Decreases the likelihood of stone formation.

Unfortunately, kidney stone evaluation is not that simple. You have to take into account the "saturation risk" of the two molecules joining. Simply stated, there is other "stuff" in the urine which may increase the likelihood of the calcium binding with the oxalate. A super-saturation profile gives us this necessary information:

| calcium --> <-- oxalate |
This urine has 1 time the risk of forming a kidney stone.

| calcium --> <-- oxalate |
This urine has 3 times the risk of forming a kidney stone — even though the amount of urine is the same as the sample above!

Therefore, I recommend you come to me for a kidney stone evaluation prior to altering your approach to reducing your kidney stones. You want to make sure you are doing the right thing prior to making a lifestyle intervention. I've seen people inadvertently INCREASE their risk, and I don't want that to happen to you.

Now we can answer the questions:

Can vitamin C lead to kidney stones?
Yes it can, but in high doses. High amounts of vitamin C increase the oxalate production in the body. Therefore, more oxalate is excreted in the urine, and in some cases the risk for kidney stones (nephrolithiasis) increases!

What about calcium supplements?
NO! Turns out that calcium when eaten with meals binds the oxalate you eat IN THE GUT, so the oxalate is less absorbed and you decrease your risk for kidney stone formation! What you have heard all these years turns out to be a myth!

Kidney Dialysis

Dr. Michael AaronsonDiamonds are forever. Is kidney dialysis? Maybe. It depends.

Patients who are hospitalized who suddenly lose the ability to make urine or detoxify their blood may only need kidney dialysis for a short period of time. Dialysis is considered a bridge so that the kidneys, which are stunned, can wake up and start working again.

On the other hand, patients who have a slow, worsening progression of their kidney function over time are less likely to recover function. These folks will likely need "kidney replacement therapy" which usually is defined as something else (like dialysis) doing the work that the kidneys would normally do.

Consider the following: most people start with 100% kidney function and 2 million "filters" to make urine and detoxify. Those who have high blood pressure and/or diabetes lose kidney function over time (the number of working filters decreases). Eventually, there aren't enough filters to clean the blood. When people have around 15% of their kidney function remaining, most need to start on kidney dialysis. Here is the bad news: for the most part kidney function stays the same or gets worse over time. It seldom gets better. Here is the good news: people either need dialysis or they don't. Many people do just fine whether they have 60% function or 100% function. So if you find out you have 60% function, your goal is to keep the kidney function where it is at and my goal is to help you do that.

There are many urban myths out there. For example, many people erroneously believe that if they "drink more water" their kidneys will get better. Unfortunately, unless you are severely dehydrated, this common belief is false. A vicious cycle occurs when you are on a water pill to get rid of fluid and you are trying to drink significant amounts of fluid to "flush" the kidneys to make them better.

Therefore, go to your primary provider and get your blood checked. Keep your weight, blood pressure, and blood sugar controlled. And if appropriate, see a kidney doctor/nephrologist sooner rather than later. I can do more for you to decrease the risk of progression of kidney failure when your kidney function is 60% as opposed to when it is 15%.

Leg Cramps

Dr. Michael Aaronson

Here's a question I frequently get from my patients:

"I have cramps in my legs. Is it due to low potassium or other electrolyte problem?"

The answer is that hypokalemia (low potassium) frequently results in leg cramps. Heart doctors see many patients with high blood pressure and heart failure. And in this setting, it is common to see these patients taking water pills to remove the excess fluid in their bodies. One of the effects of water pills (diuretics) is to decrease total body potassium. So in that setting, when patients present with leg cramps, a common cause is low potassium. And this is one of the reasons why frequent blood tests are required for patients who are prescribed diuretics—to make sure that their potassium level doesn't get too low.

Unfortunately, there is more to this story. Excessive use of diuretics leads to volume depletion, and volume depletion alone can cause leg cramps. In fact, one of the tricks kidney doctors use to determine if we have removed enough fluid during a dialysis treatment is to remove fluid until the patient starts complaining of leg cramps. Also, there are other metabolic causes of leg cramps which include diabetes, alcoholism, and hypothyroidism.

So the moral to the story is that if you are a heart patient and are on diuretics and start having muscle cramps, talk to your doctor. Regional experts in heart failure like Dr. Van De Graaff have much experience in determining the cause of the problem and providing a solution. Although low potassium is a frequent cause of leg cramps, there are many other possibilities as well. People run into problems when they try to self diagnose, change their water pill dose on their own, increase their potassium intake drastically without supervision, etc.

By the way, if you have a kidney, blood pressure, stone question, etc. that you would like answered. Please feel free to ask!

Does Too Much Soda Pop Affect the Kidneys?

Dr. Michael AaronsonI get this question a lot. In short, the answer is yes, but let me explain further. We must consider whether the soda pop is diet or not. High calorie soda equals lots of calories. Lots of calories a day equals weight gain. Drinking only one can of soda pop daily can lead to five to 10 pounds of weight gain per year. If you gain weight you are at risk for sugar diabetes. Diabetes type 2, adult onset diabetes, is the number one reason in addition to high blood pressure why peoples' kidneys fail and they need to go on kidney dialysis.

Sidebar: There was a recent study that came out which suggested that women need to exercise approximately 1 hour daily just to maintain their current weight. Therefore, in order to lose weight, you need to alter your caloric intake.

Diet soda frequently has caffeine. Caffeine is a natural diuretic, so you may urinate more, but that shouldn't adversely affect the kidneys. What most people don't appreciate, is that diet soda has a lot of sodium. Some have argued, that this makes you more thirsty. High levels of sodium in the diet lead to hypertension. As we just talked about, high blood pressure can lead to kidney failure and the need for kidney dialysis. So plain old water is the best option to quench the thirst.

Fellowship

Dr. Michael AaronsonA fellowship is the period of medical training in the United States that a physician may undertake after completing a specialty training program.

It can also be defined as "companionship of persons on equal and friendly terms."

When I was in training to become a kidney doctor at the University of Minnesota, the fellows would often partake in fellowship. Whether it was getting together for pizza or playing board games, the social time we spent helped us learn about one another outside the setting of nephrology and work. Unfortunately, as people nowadays get busier and busier, fellowship rarely happens because there is no time. Other priorities take over.

As Alegent Health continues to build a culture of excellence, fellowship is becoming a priority. Building bonds of friendship improve patient care because people work better together. Last Saturday night, my wife and I spent some quality time with our Alegent Cardiology friends and their spouses. I appreciated this opportunity, because even though I graduated 14 years ago, I'm relatively new to Omaha. Time spent playing Family Feud, Are You Smarter Than a Fifth Grader and Trivial Pursuit translated to fun, laughs and relationship building. I was thrilled my wife could get to know some of the people I work with.

I learned some interesting tidbits as well. Tara Whitmire is an advanced practice nurse who recently got accepted to the University of Iowa DNP program. The Doctor of Nursing Practice (DNP) is an advanced-level practice degree that focuses on the clinical aspects of nursing rather than academic research. The curriculum for the DNP degree generally includes advanced practice, leadership, and application of clinical research related to nursing. She starts in June and is going to get her doctorate degree. She is also really good at Family Feud. Jill Ogg-Gress has already completed her training and is a doctor of nursing practice. Dr. Joseph Thibodeau, in addition to his impressive bio, used to moonlight as an e-Focus physician while he was in training.

I am just so impressed with this group of people. They are down to earth, extremely modest, yet so well educated. There is no pomp and circumstance. And perhaps this is why they are such phenomenal clinicians with great rapport with their patients.

Did they learn anything about me? You betcha! While I was defining CPR, it came up that I set up two successful pancreas transplant programs in the Dakotas, a legacy I am quite proud of but don't usually mention.

Bottom line: Make time for fellowship. Whether it is with your co-workers, your family, or your friends, I'm sure you'll have a lot of fun!

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